- BioNano Genomics Announced the Purchase of IrysTM System by BGI
- QIAGEN partners with BGI Tech to provide services based on the Human Gene Mutation Database (HGMD) in Greater China
- BGI Tech Launches Human Whole Exome Sequencing Service on Complete Genomics’Advanced Platform
- BGI announces first flagship project with the Edinburgh Genome Foundry to synthesize the largest synthetic eukaryotic chromosome in the UK
- BGI Reports a Novel Gene for Salt Tolerance Found in Wild Soybean
- Researchers Develop a New Genome Editing Method, Bringing the Possibility of Patient-specific Gene Therapies Closer to Reality
- BGI Presents a High-quality Gene Catalog of Human Gut Microbiome, A Key to Understanding Human Health and Diseases
- BGI Reports the Evolutionary Adaptations of Tibetans May Benefited from Extinct Denisovans
- BGI Health Forms Partnership with University of Mayor in South America
- BGI Health and Sir Ganga Ram Hospital Collaborated to Introduce NIFTY Test to India
- BGI Health Joins Hand with Star Metropolis Clinical Laboratories to Provide Genetic Testing Service
- BGI-Hong Kong 3730 Production Center Begins Operating, Providing Fast and High-quality Sequencing Services
- China's genomics success shows big data challenges
- Joe Biden is wrong. China does innovate
- Mainland scientific research company BGI expands its Hong Kong operations
- BGI Plans to Sequence the World
Tel: +86-755-25031760Email: email@example.com
- The latest study was published online in Nature Genetics
June 10, 2013, Shenzhen, China - The duck genome consortium, consisted of scientists from China Agricultural University, BGI, University of Edinburgh and other institutes has completed the genome sequencing and analysis of the duck (Anas platyrhynchos), one principal natural host of influenza A viruses. This work reveals some noteworthy conclusions and provides an invaluable resource for unraveling the interactive mechanisms between the host and influenza viruses.
The new H7N9 bird flu strain killed 36 people and caused $6.5 billion loss to China’s economy. As a natural host of influenza A viruses (including H5N1), the duck is known to often remain asymptomatic under influenza infection. To uncover the interactive mechanisms between the host and influenza viruses, researchers sequenced the genome of a 10-week-old female Beijing duck, and conducted transcriptomic studies on two virus-infected ducks.
This work yielded the draft sequence of a waterfowl-duck for the first time, and the data indicated that the duck, like the chicken and zebra finch, possessed a contractive immune gene repertoire comparing to those in mammals, and it also comprises novel genes that are not present in the other three birds (chicken, zebra finch and turkey).
By comparing gene expression in the lungs of ducks infected with either highly or weakly pathogenic avian influenza H5N1 viruses, the team identified genes whose expression patterns were altered in response to avian influenza viruses. They also identify factors that may be involved in duck host immune response to avian virus infection, including the avian and mammalian -defensin gene families.
Jianwen Li, project manager from BGI, said, “This study provides very important data to better understand the interaction between the host and the avian influenza. Scientists will be able to explore more deeply the mechanisms on the spread and infection of avian influenza.”
Public Communications Officer