Asian Young Researchers to Advance Computational and Omics Biology
Publish Date: 2012-12-21

-The 6th Asian Young Researchers Conference on Computational and Omics Biology was Successfully Conducted in Shenzhen, China

December 20, 2012, Shenzhen, China – The 6th Asian Young Researchers Conference on Computational and Omics Biology (AYRCOB) is composed of six organizing countries and districts, including Australia, China, Singapore, Japan, Korea, and Taiwan. The two-day conference provides a good opportunity for young researchers to exchange views on scientific knowledge and promote the future international collaboration on computational and systems biology.

Professor Huanming Yang, Chairman of BGI delivered the opening speech entitled “Sequencing, Genomics and Future of Man”, emphasizing the importance of new technologies and collaboration. He mentioned that sequencing technology served as a robust tool to better understand life science and would bring new ways for a better future of the world. He also stressed, “The natural disasters repeatedly remind us that we are in the same family and on the same boat. If you cannot do it, collaboration can make you able to do it. If you can do it, collaboration can make it bigger and better. Only ‘win-win’ collaboration can help us build a better future.”

The keynote speaker, Dr. Yuichi Taniguchi, Unit Leader of Laboratory for Single Cell Gene Dynamics RIKEN Quantitative Biology Center, Japan, introduced their team’s work on single-cell proteome and transcriptome analyses, and the recent challenges on mRNA dynamics. He introduced that protein and mRNA often exist in low copy numbers and are difficult to detect in single cells. To cope with the difficulty, they carried out quantitative system-wide analysis in individual cells by a newly constructed yellow fluorescent protein fusion library for Escherichia coli.

With a view to improve the production of biofuel such as bio-ethanol, Dr. Binbin Chen from Nanyang Technological University, shared their study on utilizing ATP-binding cassette (ABC) in yeast to reduce the toxicity of biofuel. The toxic products such as alkanes are harmful for some beneficial microorganisms related with Biofuel production. In the conference, he introduced their approaches and latest findings, and expected that their study could be used in engineering alkane tolerance in microorganisms for better improving the production of biofuel.

In the session themed “Evolution and Genome Variation”, researchers from University of California, University of Tokyo, and Korea Advanced Institute of Science and Technology delivered a series of exciting presentations. Dr. Junko Tsuji presented a topic “Comprehensive Analysis of Mitochondrial Pseudogenes in Mammalian Genomes”, revealing several general features related to chromatin and genomic contexts in human, rhesus, mouse, and rat. Dr. Junho Kim shared their study with the attendees, and pointed out that somatic deletions may affect brain development and have a relationship with Schizophrenia.

Dr. Kai-Yao Huang and Dr. Min-Gang Su from Yuan Ze University both introduced their resource and database for protein biology. Dr. Huang mentioned that their novel method, named SplicePred, was the first online resource for the identification of RNA splicing-related proteins and it is now freely accessible via http://csb.cse.yzu.edu.tw/SplicePred/. Dr. Su introduced the database- topPTM- that integrates experimentally verified post-translational modifications (PTMs) from available databases and research articles, and annotates the PTM sites on transmembrane proteins with structural topology.

In the following day, topics will be discussed further on Network Biology, Gene Regulation and Small RNAs, and Biomedical Informatics, including presentations such as “Network Assisted Arabidopsis Systems Genetics For Studying Plant Complex Traits”, "A Functional Gene Network for Xanthomonas oryzae pv. oryzae”, "Computational Biology through Intra-relation, Inter-relation, and Integration of Diverse Genomic Data”, "Studying Small Silencing RNAs Using High Throughput Sequencing”, among others. For more information, please visit: http://2012.ayrcob.org/