Triple quadrupole mass spectrometry applications is the most sensitive and quantitative reproducibility of the best instruments. Enable high-sensitivity full-scan MS, MS/MS with high-selectivity from true triple quadrupole precursor ion (PI) and neutral loss (NL) scans. Which including Triple quadrupole mass spectrometer and QTRAP mass spectrometer.

Triple quadrupole mass spectrometer: The first (Q1) and third (Q3) quadrupoles serve as mass filters, whereas the middle (Q2) quadrupole serves as a collision cell.

QTRAP mass spectrometer: The QTRAP® platform is a unique tandem mass spectrometer which is capable of functioning as either a dedidated triple quadrupole mass spectrometer for quantitative workflows or as a highly sensitive linear ion trap mass spectrometer for qualitative workflows. The QTRAP technology can also increase selectivity by reducing interferences for quantitative applications using the MRM3 workflow in which the MRM transition is based on the MS/MS/MS fragmentation pattern of the compound of interest.

We now have AB SCIEX QTRAP® 5500QTRAP® 4500 and waters Xevo TQDXevo TQ-S.

Performance

  Mass range5~1000 Da

  Resolution:>12,000 FWHMTrap);

  Sensitiveup to 9 times increase in trapup to 100-fold increase in trap scan MS/MS sensitivity

   Scan speedup to 2400 Da/secQQQ),up to 20,000 Da/secTrap);

  Polarity switching in 50 ms

Feature

QJet® ion guide Optimized design yields better ion containment and operates at high pressure, providing better collisional focusing to enhance ion transmission for ultimate sensitivity.

The newly designed Qurved LINAC® high-pressure collision cell accelerates ions through the collision cell, increases speed of analysis and eliminates cross-talk.

 Q3 linear ion trap greatly improves the extraction efficiency to yield up to a 100 x gain in sensitivity in ion trap scan modes.

• A new and improved patented technologies fast eQ™ electronics combines with a powerful new generation of Analyst® software makes a robust, high throughput platform and a new level of quantitative performance in a reliable, easy-to-use system.

• Turbo V™ source provides high-sensitivity analysis over a wide range of flow rates with quick-change APCI and TurboIonSpray® probes.Delivering unprecedented desolvation and stability for even the toughest high-flow applications utilized to drive productivity.

Application

Designed to deliver the highest level of sensitivity and robustness for even the most complex matrices, the Triple Quad 5500 excels at multi-component quantitation.

• Environmental

• Food and beverage research

Targeted quantitative proteomics

• Identification of metabolites

Clinical research

DMPK and ADMET studies

• Proteomics research

Performance

•    Mass range5~1000 Da.

•    Resolution:>12,000 FWHMTrap.

•   SensitiveImprove MRM sensitivity by 10X vs. competitive triple quads in the same class.

  Scan speedup to 12,000 Da/sec

•   Dynamic range: achieve 5 orders

•   Polarity switching in 50 ms

Feature

• Next-generation eQ™ electronicsCompounds with vastly different functional groups can be measured in a single pass. The new electronics also provide improved ion containment for better sensitivity and superior detector performance.

• Unique MRM3 quantitation for enhanced selectivity in complex matrices.

The Turbo V™ source provides high sensitivity analysis over a wide range of flow rates with quick-change APCI and TurboIonSpray® probes(from 50 μL/min to 3 mL/min).

The patented QJet® ion guide improves ion containment and operates at high pressure, providing better collisional focusing to enhance ion transmission for ultimate sensitivity.

Applicaton

Poisons, pesticides detection and confirmation

Targeted quantitative proteomics

• Clinical research

• Newborn screening

• Vitamin D and steroids research

Performance

• Mass range: 2 to 2048 Da.

• Scan speed: Up to 10,000 Da/sec.

• Quality stability< ± 0.1 amu/24h 

Feature

Automated system checks and simplified user interface for ease-of-use.

Optimized MS/MS detection for demanding quantitative applications.

Rapid data acquisition rates for the best in accuracy and reproducibility of chromatographic peak area measurement.

Robust ZSpray™ atmospheric pressure ionization interface.

Versatile range of ionization options.

Industry-leading multimode capability in a single run.

Automated instrument optimization and quantitative method development tools.

Smallest MS/MS footprint that sits easily on your laboratory benchtop.

Application

• Regulated bioanalysis

• ADME screening

• Food safety

• Environmental monitoring

• Clinical

• Forensic Applications

• Newborn screening

• Targeted quantitative proteomics

Performance

  •  Mass range22048 Da

  •  Scan spreadup to 10,000 Da/sec

  •   Quality stability< ± 0.05 amu/24h

  •   Response liner5 orders

  •   Polarity switching in 20 ms

  •   MS to MS/MS switching in 3 ms

  •   Switching between ESI and APCI in 20ms

Feature

Engineered SimplicityTMExcellent performance and system versatility.      • StepWaveXevo TQ-S owns the unique innovation ion source technology, can improve the sensitivity level of the UPLC / MS / MS.

• ScanWaveInnovative technology to provide fast, high-quality, UPLC compatible with MS / MS data acquisition.

• RADARAn information enrichment acquisition method, can collect information about the target compound having a highly specific quantitative data, while at the same visual display of the information of all other components.

Versatility: Wide range of ionization ability adaptability, applicable to a variety of analytical applications.

Application

• Regulated bioanalysis

• ADME screening

• Food safety

• Environmental monitoring

• Clinical

• Forensic

• Newborn screening

• Targeted quantitative proteomics