Shenzhen Human commensal microorganisms and Health Research Key Laboratory based on the construction of BGI Shenzhen, established in November 2011 by Shenzhen Municipal Science and Technology Innovation Commission. The laboratory uses symbiotic microbes in the human body as the research object, relying on the advantages of a large platform and powerful sequencing analysis capabilities of BGI, focusing on the human body including the mouth, gastrointestinal tract, reproductive tract, skin and other parts of the microbial composition and microbial and human diseases, with research on the relationship between gut microbiota and health, fundamentally explain the pathogenesis of chronic metabolic diseases causes and try to make a "disease prevention, diagnosis, monitoring and improvement"model. The main research directions include: human gut microbes and dietary research, gut microbes and disease research, and metabolism of gut microbes and host, the host genotype studies.