On January 10, 2012, RainDance Technologies, Inc, the Digital Biology™ Company, today announced that it is collaborating with the Hôpital Saint-Louis in Paris, France and BGI, to discover new variants and confirm findings from a Rheumatoid Arthritis (RA) study conducted by researchers at the Hôpital Saint-Louis

On January 14, 2012, Affymetrix®, Inc (NASDAQ:AFFX), announced today that it has signed a Memorandum of Understanding (MOU) with BGI, the world’s largest genomics organization, to enter into a strategic co-development and co-marketing collaboration

On January 15, 2012, the genome of Schistosoma haematobium, a blood parasite of human, was published online in Nature Genetics It is a collaborative study led by University of Melbourne and BGI

On January 23, 2012, an analysis of the genes of twelve chimpanzees carried out by researchers at the Bioinformatics Research Centre, Aarhus University, the Section of Bioinformatics, University of Copenhagen, the Copenhagen Zoo and BGI has been published online in PNAS

On January 27, 2012, the ISA Commons – wwwisacommonsorg, is described in a Commentary published in Nature Genetics

In February, 2012, the 1KITE (1K Insect Transcriptome Evolution) project was officially started

On February 10, 2012, BGI opens its first European Genome Research Center located in Copenhagen Bio Science Park (COBIS)

On February 13, 2012, in a new study published online in Nature Biotechnology, researchers from BGI reported the evidence of extensive RNA editing in a human cell line by analysis of RNA-seq data, demonstrating the need for new robust methods to identify important post-transcriptional editing events

On February 15, 2012, VIB, one of Europe’s leading life sciences research institutes in Belgium, and BGI today concluded a jointly organized meeting focused on large-scale genomics projects

On February 17, 2012, The University of California, Davis, and BGI signed a master agreement sealing a partnership that will change the landscape of genomic sciences in California and the Western states

On February 17, 2012, BGI and Asia Cancer Research Group (ACRG) jointly announced a new collaboration on cancer genomics research as part of ACRG’s mission to generate a unique and best-in-class data source on cancers prevalent in Asia, and to accelerate research and development of improved treatments for those cancers by freely sharing the resulting data with the scientific community

On February 29, 2012, Agilent Technologies Inc (NYSE: A) and BGI today announced a collaborative effort to develop methodologies designated for next-generation genome-wide association studies

On March 2, 2012, Novo Nordisk and BGI jointly announced that they have reached an agreement to establish a global collaboration framework

On March 2, 2012, BGI developed single-cell genome sequencing technology and published two research papers for cancer single-cell sequencing in the research journal Cell

On March 3, 2012, Lal Teer Livestock Limited, an associate of Lal Teer Seed Ltd, and BGI jointly announced today that they came to a mutual agreement to conduct collaborative water buffalo genome sequencing and bioinformatics analysis

On March 7, 2012, the 13th Workshop of Genomic Standard Consortium Meeting organized by BGI, and the Genomic Standard Consortium (GSC) was successfully conducted at Kingkey Palace Hotel, Shenzhen, China

On March 8, 2012, BGI reported that it can use next-generation sequencing to analyze DNA as low as 200 ng from formalin-fixed paraffin-embedded (FFPE) samples

On March 21, 2012, to facilitate the genomics research and communication between BGI, University of Helsinki and Wuhan University, researchers from these organizations have reached a Memorandum of Understanding setting forth a framework for some subjects of mutual interest in the field of genomics, such as archaeal organisms from hypersaline environments, among others

On March 23, 2012, BGI, Technological Top Institute of Green Genetics, Netherlands eScience Centre and Netherlands Institute of Bioinformatics signed a Memorandum of Understanding to address the challenge of managing, transporting, integrating and analysing today’s tremendous flow of genomic data

On March 25, 2012, BGI has launched a joint bioinformatics & computing laboratory with National Supercomputing Center in Tianjin (NSCC-TJ) to promote the interdisciplinary cooperation in the fields of supercomputing and biological science as well as to boost the rapid development of OMICS-related industries

On April 17, 2012, the international coordination meeting on the synthetic yeast project (Sc20 PROJECT), co-organized by Johns Hopkins University, BGI and Tsinghua University with the support of National Science Foundation, was held at the Wenjin Hotel, Beijing, China

On April 19, 2012, Chinese scientists from BGI, together with the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences and Shihezi University, Xinjiang province, made a significant breakthrough in animal cloning The world’s first transgenic sheep produced with a simplified technique, handmade cloning, was successfully born in Xinjiang Uygur Autonomous Region, China

On April 19, 2012, The 2012 Autism Symposium on Genetic and Epidemiology Research, organized by BGI, One Foundation, and co-organized by Autism Speaks, was held in Shenzhen

On April 24, 2012, BGI and the International Crops Research Institute for the Semi-Arid Tropics jointly announced the signing of a Memorandum of Understanding for a long-term collaboration on applied genomics research and molecular breeding

On April 24, 2012, BGI introduced its latest-generation cloud-based Software as a Service (SaaS) solution, EasyGenomics™, at the 10th Bio-IT World Conference & Expo being held April 24 to 26 in Boston, Mass

On April 25, 2012, Aspera, Inc and BGI announced at Bio-IT World that they have partnered to integrate and deploy the Aspera Connect Server and Aspera fasp™ high-speed file transferring technology with “EasyGenomicsTM”, BGI’s latest cloud-based Software as a Service (SaaS) platform, and to expand BGI’s high speed sequencing data delivery service

On May 2, 2012, representatives from BGI, in conjunction with George Mason University, the Massachusetts Eye and Ear Infirmary and the University of Oklahoma Health Sciences Center, jointly announce that they have signed an agreement to sequence 100 human adenoviruses gathered from researchers globally, including ones that cause respiratory, gastrointestinal and ocular diseases

On May 11, 2012, The 2nd Japan-China Symposium on Cancer Research, jointly organized by Chiba Cancer Center, Tokyo Medical and Dental University, BGI, and BGI JAPAN, was successfully held on May 9th-11th, 2012 in Chiba, Japan

On May 14, 2012, BGI, in cooperation with Zhangjiakou Academy of Agricultural Science, has completed the genome sequence and analysis of foxtail millet (Setaria italica), the second-most widely planted species of millet Results of the latest study were published online in Nature Biotechnology

On May 15, 2012, BGI announced that a new Roche GS FLX+ System has been successfully installed at its facility in Shenzhen, China

On May 16, 2012, The Children’s Hospital of Philadelphia and China National GeneBank (Shenzhen) sealed a Memorandum of Understanding (MOU) for collaboration on BioBank

On May 22, 2012, in a paper published online in Nature Communications, researchers from Sichuan Agricultural University and BGI reported the atlas of DNA methylomes in porcine adipose and muscle tissues, providing a valuable epigenomic source for obesity prediction and prevention as well as boosting the further development of pig as a model animal for human obesity research

On May 24, 2012, Nature Publishing Group published Nature Publishing Index (NPI) 2011 China, a supplement to Nature BGI Shenzhen is ranked 10th of Top 10 Institutions in the index

On May 26, 2012, The International Conference on Genomics in Europe (ICG-Europe), organized by BGI, was successfully conducted at Biocenter of Copenhagen, Denmark

On May 28, 2012, The Asian Cancer Research Group, in collaboration with BGI, announced the publication of results from a whole genome-wide study of recurrent hepatitis B virus (HBV) integration in hepatocellular carcinoma (HCC) in Nature Genetics

On June 4, 2012, BGI, together with other 17 international institutes, announced that they completed the second generation of maize HapMap (Maize HapMap2) and genomics studies on maize domestication and improvement The two separate studies were published online in the same issue of Nature Genetics

On June 4, 2012, the workshop themed “High--throughput Genomics: a Revolution in the Life Sciences” was successfully held in Utrecht, the Netherlands The workshop was co-organized by Utrecht University, the University Medical Center Utrecht and BGI

On June 6, 2012, an international pear genome consortium, including scientists from Nanjing Agricultural University, BGI, Zhejiang Academy of Agricultural Sciences, University of Illinois at Urbana-Champaign, University of Georgia, University of Hawaii, and Tohoku University, has completed the first pear genomic sequence in the world The early access of pear genomic data is now available online (http://peargenomenjaueducn)

On June 11, 2012, an international study, conducted by Bellvitge Biomedical Research Institute (IDIBELL), BGI, and other collaborators, demonstrates that the DNA methylomes between newborns and centenarians are different, shedding important new light on how epigenetic marks degrade during aging The latest study was published online in the National Academy of Sciences (PNAS)

On June 12, 2012, GE Healthcare, the healthcare business of GE (NYSE: GE), and BGI jointly announced today a pioneering multi-year research collaboration in stem cell science

On June 18, 2012, BGI and The Children’s Hospital of Philadelphia (CHOP) today announced that they have jointly initiated the 1,000 Rare Diseases Project with the aim of accelerating the discovery of genetic variants underlying rare diseases

On June 29, 2012, BGI announced today that a group of scientists and researchers successfully demonstrated genomic data transfer at a sustained rate of almost 10 Gigabits per second (Gbps) over a new link connecting US and China research and education networks

On July 3, 2012, the symposium themed “The Era of Next Generation Sequencing in Cancer”, co-organized by BGI and Imperial College London, was successfully conducted in London, UK

On July 5, 2012, an international team, led by Lanzhou University, comprising BGI, Institute of Kunming Zoology, Chinese Academy of Sciences as well as the other 12 institutes, has completed the genomic sequence and analyses of a female domestic yak, which provides important insights into understanding mammalian divergence and adaptation at high altitude This study was recently published online in Nature Genetic

On July 12, 2012, BGI and their publishing partner BioMed Central, a leader in scientific data sharing, announce the launch of a new journal, GigaScience, which publishes large-scale biological research in a unique format

On July 13, 2012, an international team, led by Institute of Genetics and Developmental Biology, Chinese Academy of Science and BGI, has completed the genomic sequence and analysis of salt cress (Thellungiella salsuginea), a wild salt-tolerant plant The study was published online in PNAS

On July 17, 2012, BGI announced today that it has successfully developed a new filtering tool, PDXomics™, which performs accurate and specific classification of the mixed reads derived from the host and tumor xenografts

On July 24, 2012, a memorandum of understanding was signed between the University of Edinburgh and BGI

On July 30, 2012, a five-country international team, led by Casey Eye Institute Molecular Diagnostic laboratory, BGI and Zhejiang University School of Medicine First Affiliated Hospital identified the NMNAT1 mutations as a cause of Leber congenital amaurosis (LCA), one of the most common causes of inherited blindness in children The latest study was published online in Nature Genetics

On August 1, 2012, The University of Birmingham and BGI have announced a major joint initiative in environmental and human health research

On August 7, 2012, BGI Tech Solutions Co, LTD and BGI Ark Biotechnology Co, LTD today announced that they have jointly developed an advanced transgenic mice platform for boosting human diseases and medical research, with the advantages of improved efficiency, high positive rate, available sex determination, fast turnaround time, and low cost

On August 21, 2012, the three-day conference themed “Fourth Symposium & Short Course on Medical and Laboratory Applications of Genetics and Genomics (Special Section for inherited Eye Diseases)” was successfully conducted in Shenzhen China

On August 22, 2012, an international team led by New York University School of Medicine and BGI has completed the first genome-wide and single-nucleotide resolution DNA methylomes of two ant species: Camponotus floridanus and Harpegnathos saltator The latest study was published in Current Biology, one sister journal of Cell

On August 28, 2012, the international research team led by Chinese Academy of Agricultural Sciences and BGI has completed the genome sequence and analysis of a diploid cotton-- Gossypium raimondii The study was published online in Nature Genetics

On September 17, 2012, Complete Genomics, Inc (NASDAQ: GNOM), and BGI-Shenzhen announced that they have entered into a definitive merger agreement Through this agreement, a wholly-owned US subsidiary of BGI will launch a tender offer to purchase all outstanding shares of common stock of Complete for $315 per share in cash, without interest

On September 17, 2012, a Chinese research team, led by Anhui Medical University and BGI, has found the strong genetic evidences of mevalonate kinase gene (MVK) mutations link to disseminated superficial actinic porokeratosis (DSAP) The latest study was published online in Nature Genetics

On September 18, 2012, BGI Tech Solutions Co, Ltd, a subsidiary company of BGI, announced that they have achieved whole exome sequencing analysis of total degraded DNA as low as 200 ng from formalin fixed paraffin embedded (FFPE) samples

On September 20, 2012, an international research team, led by Institute of Oceanology of Chinese Academy of Sciences and BGI, has completed the sequencing, assembly and analysis of Pacific oyster (Crassostrea gigas) genome—the first mollusk genome to be sequenced—that will help to fill a void in our understanding of the species-rich but poorly explored mollusc family The study was published online in Nature

On September 24, 2012, BGI announced that it and INEX Innovations Exchange Pte Ltd have formed a partnership to establish a Next Generation Sequencing (NGS) facility in Singapore to offer a suite of molecular genetics tests, starting with a non-invasive fetal trisomy (NIFTY) test to detect fetal chromosomal abnormalities in pregnant women

On September 24, 2012, BGI and Griffith University jointly announced that they came into a mutual agreement to conduct collaborations in teaching, training, research and other activities

On September 25, 2012, BGI announced that it and the Bill & Melinda Gates Foundation have signed a Memorandum of Understanding (MOU) to form a collaboration on global health and agricultural development with the goal of achieving common objectives in health and agricultural development, and meaningfully contributing to the achievement of one or more of the Millennium Development Goals

On September 26, 2012, BGI announces the online publication in the international journal Nature of a novel metagenomic study on human gut microbiota and their potential impact on type 2 diabetes (T2D), the most common form of diabetes

On September 27, 2012, The Children’s Hospital of Philadelphia and BGI announced that the BGI@CHOP Joint Genome Center will begin to offer clinical next-generation sequencing (NGS) services at CHOP through the hospital’s Department of Pathology and Laboratory Medicine in a CAP/CLIA-compliant environment

On September 28, 2012, the inaugural International Conference on Genomics in the Americas (ICG Americas 2012), co-organized by BGI and the Children’s Hospital of Philadelphia (CHOP), was successfully concluded with numerous updates

On October 16, 2012, BGI and GENNET jointly announced that they have entered a collaborative agreement on non-invasive fetal trisomy (NIFTY) test with the aim to significantly improve reproductive health in Czech and Slovak Republics

In October 2012, five major data centres have expanded their commitment to make research data more accessible through the British Library’s DataCite service, a global initiative that addresses the problem of how to find, access and re-use the results of research BGI is the first Asian data centre, alongside the UK based Archaeology Data Service, the UK Data Archive, the Natural Environment Research Council, the Science & Technology Facilities Council that have signed up to the service and are the first institutions to work with the British Library on this initiative

On October 31, 2012, Cambridge, MA, and Shenzhen, China – BGI, the world’s largest genomics organizations, announced today it is among 101 research organizations comprising the 1000 Genomes Project Consortium that has successfully constructed an integrated map of genetic variation from 1,092 human genomes, providing an invaluable resource for researchers to better understand the contribution of genetics to diseases The latest study was published as an Advance Online Publication in Nature

On November 15, 2012, today marks the publication of two studies involving researchers from the BGI on the whole-genome sequencing, analysis and production of high quality reference genomes for the pig in the journals Nature and GigaScience (a BGI and BioMed Central journal)

On November 19, 2012, an international research team led by Nanjing Agricultural University and BGI, has completed the first genomic sequence of pear by an approach using the combination of BAC-by-BAC strategy and next-gen sequencing The results were published online in Genome Research

On November 20, 2012, BGI-Shenzhen announced that it, through its wholly-owned subsidiary Beta Acquisition Corporation, has extended its all cash tender offer to purchase all outstanding shares of common stock of Complete Genomics, Inc (GNOM) to 12:00 midnight (New York City time) on Friday, December 14, 2012 The Offer was previously scheduled to expire at 12:00 midnight (New York City time) on Wednesday, November 21, 2012

On November 26, 2012, an international team led by Beijing Academy of Agriculture and Forestry Sciences, BGI, and other institutes has completed the genomic sequence of watermelon (Citrullus lanatus) and the resequencing of 20 watermelon accessions

On November 28, 2012, BGI announced its latest advances in the analysis, management and dissemination of “Big Genomics Data” at their 3rd bioinformatics software and data release conference

On December 1, 2012, BGI announced the establishment of BGI Hong Kong Research Institute and the appointment of five honorary professors in the 7th International Conference on Genomics & Bio-IT APAC 2012

On December 3, 2012, The 7th International Conference on Genomics and Bio-IT APAC 2012, organized by BGI, successfully concluded with numerous updates on on-going research applying today's latest sequencing and bioinformatics technologies to a new paradigm of human diseases and to enhancing global agriculture development

On December 13, 2012, the first Shenzhen International Biotech Innovation Forum & Expo (SIBIFE), co-organized by Shenzhen Municipal people’s Government, China Medicinal Biotechnology Association and BGI, is being held from December 13 to December 15 at Shenzhen Convention and Exhibition Center

On December 16, 2012, a research team, led by Institute of Zoology of Chinese Academy of Sciences and BGI, has successfully reconstructed a continuous population history of the giant panda from its origin to the presentThe latest study was published online in Nature Genetics

On December 17, 2012, The 2012 ISCB-Asia/SCCG, a joint-event of ISCB-Asia 2012 and the Shenzhen Conference on Computational Genomics (SCCG), is co-organized by International Society for Computational Biology (ISCB) and BGI

On December 20, 2012, The 6th Asian Young Researchers Conference on Computational and Omics Biology (AYRCOB) is composed of six organizing countries and districts, including Australia, China, Singapore, Japan, Korea, and Taiwan

On December 21, 2012, an international team, comprised King’s College London, Pfizer, BGI and other organizations, has explored the genetic variation related with pain sensitivity in the normal population, revealing some existing discovery that treatments for high blood pressure may also be used to treat chronic pain in the future The latest study was published online in the international journal PLoS Genetics

On December 21, 2012, a study published online in Cell reports the latest investigation of de novo germline mutation by whole genome sequencing in autism patients

On December 21, 2012, BGI announces the online publication in Science of the latest findings through genomic analysis of two distantly related bat species, the Black flying fox (Pteropus alecto) and David’s Myotis (Myotis davidii)

On December 24, 2012, in a collaborative study published online today in Nature Biotechnology, researchers from Kunming Institute of Zoology, Chinese Academy of Sciences, BGI, and other institutes, have completed the first genome sequence of domestic goat by a robust approach integrated with next-generation sequencing (NGS) and whole-genome mapping (WGM) technologies

On December 28, 2012, BGI-Shenzhen and Complete Genomics, Inc announced that they have obtained clearance from the Committee on Foreign Investment in the United States regarding BGI’s proposed acquisition of Complete pursuant to the previously announced Agreement and Plan of Merger, dated as of September 15, 2012, among BGI, Beta Acquisition Corporation and Complete

On December 28, 2012, a Chinese research team, led by Beijing Forestry University, BGI, Beijing Lin Fu Ke Yuan Flowers Co, Ltd, and other institutes, has completed the first genomic sequence of Prunus mume, known as mei